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Article

Effects of Chain-Chain Associations on Hybridization in DNA Brushes.

Langmuir : the ACS journal of surfaces and colloids - 6 Dec 2016

Chiang Hao-Chun, Levicky Rastislav

Abstract excerpt

Hybridization of solution nucleic acids to DNA brushes is widely encountered in diagnostic and materials science applications. Typically, brush chain lengths of ten or more nucleotides are used to provide the needed sequence specificity and binding affinity. At these lengths, coincidental occurrence of complementary regions is expected to lead to associations between the nominally single-stranded brush chains due...

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PMID: 27934512
DOI: 10.1021/acs.langmuir.6b02990

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