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Article

Precise identification of a human immunodeficiency virus type 1 antigen processing mutant.

Journal of virology - 1 Feb 2007

Zimbwa Peter, Milicic Anita, Frater John, Scriba Thomas J, Willis Antony, Goulder Philip J R, Pillay Tilly, Gunthard Huldrych, Weber Jonathan N, Zhang Hua-Tang, Phillips Rodney E

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) evokes a strong immune response, but the virus persists. Polymorphisms within known antigenic sites result in loss of immune recognition and can be positively selected. Amino acid variation outside known HLA class I restricted epitopes can also enable immune escape by interfering with the processing of the optimal peptide antigen. However, the lack of precise rules...

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Share to Antigens, Viral
Share to Epitopes, T-Lymphocyte

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HIV Infections

Share to HIV Reverse Transcriptase

Share to HLA-B Antigens

Share to Leukocytes, Mononuclear

Share to T-Lymphocytes, Cytotoxic

Source

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Identifiers

PMID: 17108020
DOI: 10.1128/JVI.00968-06
PMCID: PMC1797578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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