Article
Multiple T-cell epitopes overlap positively-selected residues in the p1 spacer protein of HIV-1 gag.
AIDS (London, England) - 27 Apr 2009
Semeniuk Christina A, McKinnon Lyle, Peters Harold O, Gubbins Michael, Mao Xiaojuan, Ball Terry B, Luo Ma, Plummer Francis A
Abstract excerpt
OBJECTIVES: The p1 region of HIV-1 gag contains the frameshift stem-loop, gag-pol transframe and a protease cleavage site that are crucial for viral assembly, replication and infectivity. Identifying and characterizing CD8+ epitopes that are under host immune selection in this region will help in...
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