Article
Identification and characterization of HLA-A*0301 epitopes in HIV-1 gag proteins using a novel approach.
Journal of immunological methods - 31 Jan 2010
Semeniuk Christina A, Capina Rupert E, Mendoza Mark G R, Kimani Joshua, Ball T Blake, Luo Ma, Plummer Francis A
Abstract excerpt
Identification of CTL epitopes correlated to immune protection is important for the development of vaccines that enhance T-cell mediated immune responses. The correlation of positively selected amino acids (PS) of HIV-1 with host HLA alleles can identify regions containing potential T-cell epitopes. However, the specific epitopes have to be identified and characterized using overlapping peptides through T-cell...
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