Article
Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1.
Circulation research - 24 Nov 2006
Keller Tymen T, van der Sluijs Koen F, de Kruif Martijn D, Gerdes Victor E A, Meijers Joost C M, Florquin Sandrine, van der Poll Tom, van Gorp Eric C M, Brandjes Dees P M, Büller Harry R, Levi Marcel
Abstract excerpt
Influenza infections increase the risk of diseases associated with a prothrombotic state, such as venous thrombosis and atherothrombotic diseases. However, it is unclear whether influenza leads to a prothrombotic state in vivo. To determine whether influenza activates coagulation, we measured coa...
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