Article

Complement Regulator Factor H is a Cofactor for Thrombin in both Pro- and Anticoagulant Roles

2021-07-23

Abstract excerpt

<h4>Background</h4> Complement FH (FH) is a key regulator of complement activity whereas thrombin (FIIa) is central to hemostasis with both pro- and anticoagulant functions. Both have separately been shown to have auxiliary activities across the two systems. The purpose of this study was to determine the effect of FH on pro- and anti-coagulant functions and investigate the interaction between FH and thrombin. <h4...

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Literature Corpus work: 173b9d96-08a2-5f76-bb59-7806df735744
DOI: 10.1101/2021.07.22.452893

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