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Influenza A H1N1 Infection Triggers Endothelial Immunothrombosis via TNF-α–Tissue Factor–Thrombin Signaling in Human Brain Microvascular Endothelial Cells

2026-08-26

Abstract excerpt

Severe Influenza A virus (IAV) infection is associated with endothelial dysfunction, inflammation, and coagulation abnormalities. However, the mechanisms linking endothelial inflammatory activation to thrombosis remain incompletely understood. We investigated whether Influenza A/H1N1 induces an immunothrombotic phenotype in human brain microvascular endothelial cells. We infected HBEC-5i cells with Influenza A/H1N...

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Literature Corpus work: 60538d55-e69a-5d5c-8786-191b6e47bebe
DOI: 10.20944/preprints202608.1918.v1

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