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Article

Nucleotide change of codon 38 in the X gene of hepatitis B virus genotype C is associated with an increased risk of hepatocellular carcinoma.

Journal of hepatology - 1 Dec 2006

Muroyama Ryosuke, Kato Naoya, Yoshida Haruhiko, Otsuka Motoyuki, Moriyama Masaru, Wang Yue, Shao Run-Xuan, Dharel Narayan, Tanaka Yasuo, Ohta Miki, Tateishi Ryosuke, Shiina Shuichiro, Tatsukawa Masashi, Fukai Kenichi, Imazeki Fumio, Yokosuka Osamu, Shiratori Yasushi, Omata Masao

Abstract excerpt

BACKGROUND/AIMS: The hepatitis B virus (HBV) genotype C is associated with the development of hepatocellular carcinoma (HCC). In addition, the HBV X gene, which encodes the pleiotropic transactivator HBx, has also been associated with the development of HCC. In this study, we investigated whether nucleotide changes in the X gene of genotype C are associated with the development of HCC. METHODS/RESULTS: We...

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Identifiers

PMID: 17050029
DOI: 10.1016/j.jhep.2006.07.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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