Identification of hepatitis B virus X gene mutation in Hong Kong patients with hepatocellular carcinoma.

doi:10.1016/j.jcv.2005.01.006

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Article

Identification of hepatitis B virus X gene mutation in Hong Kong patients with hepatocellular carcinoma.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Sept 2005

Chen G G, Li M Y, Ho R L K, Chak E C W, Lau W Y, Lai P B S

Abstract excerpt

BACKGROUND: Chronic infection by hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC) in man. The viral transactivator HBV X (HBx) gene plays a critical role in the molecular pathogenesis of HBV-related HCC. OBJECTIVES: The aim of this study was to investigate whether th...

Topics

Base Sequence
Carcinoma, Hepatocellular
DNA Primers
DNA Transposable Elements
DNA, Viral
Genes, Viral
Hepatitis B
Hong Kong
Humans
Liver Neoplasms
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Single Nucleotide
Risk
Trans-Activators
Viral Regulatory and Accessory Proteins

Source

Open in PubMed

Identifiers

PMID: 16087118
DOI: 10.1016/j.jcv.2005.01.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-16087118-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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