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Article

Mutations within the hepatitis B virus genome among chronic hepatitis B patients with hepatocellular carcinoma.

Journal of medical virology - 1 Sept 2003

Bläckberg Jonas, Kidd-Ljunggren Karin

Abstract excerpt

Chronic hepatitis B infection is a major cause of hepatocellular cancer (HCC). The pathogenesis of the carcinogenesis is not fully understood. Viral proteins such as the X protein and the truncated middle S protein have been implicated to be transactivators. In order to investigate whether any mutations within relevant parts of the hepatitis B virus (HBV) genome could be associated with the development of HCC,...

Topics

Adult
Aged
Aged, 80 and over
Carcinoma, Hepatocellular
Female
Genes, Viral
Genome, Viral
Genotype
Hepatitis B virus
Hepatitis B, Chronic
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Promoter Regions, Genetic

Source

Identifiers

PMID: 12858404
DOI: 10.1002/jmv.10458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12858404-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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