Genomic change in hepatitis B virus associated with development of hepatocellular carcinoma.

doi:10.3748/wjg.v22.i23.5393

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Article

Genomic change in hepatitis B virus associated with development of hepatocellular carcinoma.

World journal of gastroenterology - 21 Jun 2016

Lee Danbi, Lyu Heather, Chung Young-Hwa, Kim Jeong A, Mathews Priya, Jaffee Elizabeth, Zheng Lei, Yu Eunsil, Lee Young Joo, Ryu Soo Hyung

Abstract excerpt

AIM: To determine the genomic changes in hepatitis B virus (HBV) and evaluate their role in the development of hepatocellular carcinoma (HCC) in patients chronically infected with genotype C HBV. METHODS: Two hundred and forty chronic hepatitis B (CHB) patients were subjected and followed for a median of 105 mo. HCC was diagnosed in accordance with AASLD guidelines. The whole X, S, basal core promoter (BCP), and...

Topics

Adult
Aged
Aged, 80 and over
Carcinoma, Hepatocellular
DNA, Viral
Female
Follow-Up Studies
Genotype
Hepatitis B Core Antigens
Hepatitis B Surface Antigens
Hepatitis B virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatitis B, Chronic

Humans

Liver Neoplasms

Male

Middle Aged

Mutation

Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 27340355
DOI: 10.3748/wjg.v22.i23.5393
PMCID: PMC4910660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27340355-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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