Hepatitis B virus X mutations occurring naturally associated with clinical severity of liver disease among Korean patients with chronic genotype C infection.

doi:10.1002/jmv.21219

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Article

Hepatitis B virus X mutations occurring naturally associated with clinical severity of liver disease among Korean patients with chronic genotype C infection.

Journal of medical virology - 1 Aug 2008

Kim Hyun-Ju, Park Joo-Hee, Jee Youngmee, Lee Seoung-Ae, Kim Hong, Song Byung-Cheol, Yang Soohyun, Lee Myunghee, Yoon Jung-Hwan, Kim Yoon Jun, Lee Hyo-Suk, Hwang Eung-Soo, Kook Yoon-Hoh, Kim Bum-Joon

Abstract excerpt

Few reports have detailed mutation frequencies and mutation patterns in the entire X region according to clinical status. The aims of this study were to elucidate the relationships between mutation patterns and their frequencies in the X region and clinical status in a Korean cohort and determine specific X mutation types, related closely with liver disease progression. All X mutations were determined by direct...

Topics

Adult
Aged
Amino Acid Sequence
Carcinoma, Hepatocellular
Female
Genotype
Hepatitis B virus
Hepatitis B, Chronic
Humans
Korea

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Cirrhosis

Male

Middle Aged

Molecular Sequence Data

Mutation

Prevalence

Severity of Illness Index

Trans-Activators

Source

Open in PubMed

Identifiers

PMID: 18551606
DOI: 10.1002/jmv.21219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-18551606-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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