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Article

Vitamin D inhibits the formation of prostatic intraepithelial neoplasia in Nkx3.1;Pten mutant mice.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2006

Banach-Petrosky Whitney, Ouyang Xuesong, Gao Hui, Nader Kamyar, Ji Yan, Suh Nanjoo, DiPaola Robert S, Abate-Shen Cory

Abstract excerpt

PURPOSE: Epidemiologic studies have shown that reduced levels of vitamin D represent a major risk factor for prostate cancer. In this report, we have examined the efficacy of 1alpha,25-dihydroxyvitamin D(3) (1,25 D(3)) as a chemopreventive agent using Nkx3.1; Pten mutant mice, which recapitulate stages of prostate carcinogenesis from prostate intraepithelial neoplasia (PIN) to adenocarcinoma. EXPERIMENTAL DESIGN:...

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PMID: 17020998
DOI: 10.1158/1078-0432.CCR-06-1039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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Vitamin D inhibits the formation of prostatic intraepithelial neoplasia in Nkx3.1;Pten mutant mice.PMID 17020998Read ↗

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