Article
Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice.
Cancer research - 15 Aug 2006
Gao Hui, Ouyang Xuesong, Banach-Petrosky Whitney A, Shen Michael M, Abate-Shen Cory
Abstract excerpt
Although androgen deprivation therapy is a widely used treatment for patients with advanced prostate cancer, it ultimately results in the emergence of a hormone-refractory disease that is invariably fatal. To provide insights into the genesis of this disease, we have employed an in vivo model to...
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