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Article

DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth.

Molecular and cellular biology - 1 Oct 2006

Wu Kongming, Li Anping, Rao Mahadev, Liu Manran, Dailey Vernon, Yang Ying, Di Vizio Dolores, Wang Chenguang, Lisanti Michael P, Sauter Guido, Russell Robert G, Cvekl Ales, Pestell Richard G

Abstract excerpt

Obstacles to the expansion of cells with proliferative potential include the induction of cell death, telomere-based senescence, and the pRb and p53 tumor suppressors. Not infrequently, the molecular pathways regulating oncogenesis recapitulate aberrations of processes governing embryogenesis. The genetic network, consisting of the dachshund (dac), eyes absent (eya), eyeless, and sine oculis (so) genes, regulates...

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Identifiers

PMID: 16980615
DOI: 10.1128/MCB.00268-06
PMCID: PMC1592900

Genes

DACH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth.PMID 16980615Read ↗

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Cell Fate Factor DACH1 Represses YB-1–Mediated Oncogenic Transcription and TranslationSemantic proximity Read ↗

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