Article

EYA4 drives breast cancer progression and metastasis through its novel role in replication stress avoidance.

2023-05-15

Abstract excerpt

The Eyes Absent (EYA) family of proteins is an atypical group of four dual-functioning protein phosphatases, which have been linked to many vital cellular processes and organogenesis pathways. Like the other isoforms, EYA4 possesses transcriptional activation and phosphatase functions, with serine/threonine and tyrosine phosphatase domains. EYA4 has been associated with several human cancers, with tumor-suppressin...

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Literature Corpus work: 012e018a-856f-5177-a80b-667baac597a5
DOI: 10.21203/rs.3.rs-2917471/v1

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