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Article

Visualizing the assembly of human Rad51 filaments on double-stranded DNA.

Journal of molecular biology - 27 Oct 2006

Prasad Tekkatte Krishnamurthy, Yeykal Caitlyn C, Greene Eric C

Abstract excerpt

Rad51 is the core component of the eukaryotic homologous recombination machinery and assembles into extended nucleoprotein filaments on DNA. To study the dynamic behavior of Rad51 we have developed a single-molecule assay that relies on a combination of hydrodynamic force and microscale diffusion barriers to align individual DNA molecules on the surface of a microfluidic sample chamber that is coated with a lipid...

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Identifiers

PMID: 16979659
DOI: 10.1016/j.jmb.2006.08.046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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