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Article

No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence.

Psychiatric genetics - 1 Oct 2006

Weller Andrew E, Dahl John P, Lohoff Falk W, Kampman Kyle M, Oslin David W, Dackis Charles, Ferraro Thomas N, O'Brien Charles P, Berrettini Wade H

Abstract excerpt

OBJECTIVE: A number of studies have investigated the genes underlying dopamine, serotonin, and glutamine neurotransmitter systems in order to find a genetic basis for the pathology of cocaine dependence. The gene that encodes the prostate apoptosis factor-4 (Par-4) protein is located in the 12q21 region and has been shown to directly interact with the D2 dopamine receptor and through such interaction is thought...

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PMID: 16969273
DOI: 10.1097/01.ypg.0000218618.73257.8d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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