Article
Novel and previously reported single-nucleotide polymorphisms in the human 5-HT(1B) receptor gene: no association with cocaine or alcohol abuse or dependence.
American journal of medical genetics - 8 Aug 2001
Cigler T, LaForge K S, McHugh P F, Kapadia S U, Leal S M, Kreek M J
Abstract excerpt
Evidence from animal self-administration and human genetics studies suggests that the serotonin(1B) (5-HT(1B)) receptor may be involved in modulating responses to cocaine or alcohol. We hypothesize that polymorphisms, including single-nucleotide polymorphisms (SNPs), in the human 5-HT(1B) receptor gene, may be associated with individual differences in vulnerability to cocaine or alcohol abuse or dependence. A...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
