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Article

No association between D2 dopamine receptor (DRD2) alleles or haplotypes and cocaine dependence or severity of cocaine dependence in European- and African-Americans.

Biological psychiatry - 1 Feb 1999

Gelernter J, Kranzler H, Satel S L

Abstract excerpt

BACKGROUND: Association studies between marker alleles at the D2 dopamine receptor gene (DRD2) and various psychiatric illnesses have produced conflicting results. Reports of allelic associations were originally made with alcoholism, but were then extended to other psychiatric disorders; there has been a series of positive reports suggesting an association between DRD2 alleles and substance dependence in...

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Source

Identifiers

PMID: 10023512
DOI: 10.1016/s0006-3223(97)00537-4

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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No association between D2 dopamine receptor (DRD2) alleles or haplotypes and cocaine dependence or severity of cocaine dependence in European- and African-Americans.PMID 10023512Read ↗

D2 dopamine receptor gene (DRD2) allele and haplotype frequencies in alcohol dependent and control subjects: no association with phenotype or severity of phenotype.Semantic proximity Read ↗

Association analysis between polymorphisms in the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes with cocaine dependence.Semantic proximity Read ↗

Family-based study of DRD2 alleles in alcohol and drug dependence.Semantic proximity Read ↗

The D2 dopamine receptor gene: a review of association studies in alcoholism and phenotypes.Semantic proximity Read ↗

No association between an allele at the D2 dopamine receptor gene (DRD2) and alcoholism.Semantic proximity Read ↗

Allelic association of the D2 dopamine receptor gene with cocaine dependence.Semantic proximity Read ↗

The dopamine D2 receptor gene: a genetic risk factor in substance abuse.Semantic proximity Read ↗

No association between D2 dopamine receptor (DRD2) "A" system alleles, or DRD2 haplotypes, and posttraumatic stress disorder.Semantic proximity Read ↗

The D2 dopamine receptor gene, addiction, and personality: clinical correlates in cocaine abusers.Semantic proximity Read ↗

Haplotypes at the DRD2 locus and severe alcoholism.Semantic proximity Read ↗

Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations.Semantic proximity Read ↗

Dopamine D2 receptor (DRD2) genotype differentiates intravenous drug abusers from alcoholics and non-abusers.Semantic proximity Read ↗

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