Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of dopamine receptor D4 variation on alcohol and tobacco use and on novelty seeking: multivariate linkage and association analysis.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2004

Luciano Michelle, Zhu G, Kirk K M, Whitfield J B, Butler R, Heath A C, Madden P A F, Martin N G

Abstract excerpt

The dopamine D4 receptor gene contains a polymorphic sequence consisting of a variable number of 48-base-pair (bp) repeats, and there have been a number of reports that this polymorphism is associated with variation in novelty seeking or in substance abuse and addictive behaviors. In this study w...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Australia
Share to Drinking Behavior

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multivariate Analysis

Share to Receptors, Dopamine D2

Share to Receptors, Dopamine D4

Share to Twins, Dizygotic

Share to Twins, Monozygotic

Source

Identifiers

PMID: 14681925
DOI: 10.1002/ajmg.b.20077

Genes

DRD4
ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14681925-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of dopamine receptor D4 variation on alcohol and tobacco use and on novelty seeking: multivariate linkage and association analysis.PMID 14681925Read ↗

No association between novelty seeking and the type 4 dopamine receptor gene (DRD4) in two New Zealand samples.Semantic proximity Read ↗

The dopamine D Receptor (DRD4) gene exon III polymorphism, problematic alcohol use and novelty seeking: direct and mediated genetic effects.Semantic proximity Read ↗

D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects.Semantic proximity Read ↗

DRD4 and novelty seeking: results of meta-analyses.Semantic proximity Read ↗

The association of DRD4 and novelty seeking is found in a nonhuman primate model.Semantic proximity Read ↗

Personality traits and dopamine receptors (D2 and D4): linkage studies in families of alcoholics.Semantic proximity Read ↗

Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking.Semantic proximity Read ↗

Novelty seeking and the dopamine D4 receptor gene (DRD4) revisited in Asians: haplotype characterization and relevance of the 2-repeat allele.Semantic proximity Read ↗

The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus.Semantic proximity Read ↗

Association between novelty seeking and the type 4 dopamine receptor gene in a large Finnish cohort sample.Semantic proximity Read ↗

Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics.Semantic proximity Read ↗

Novelty seeking involved in mediating the association between the dopamine D4 receptor gene exon III polymorphism and heavy drinking in male adolescents: results from a high-risk community sample.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.