Article
Association study of dopamine D2 and D3 receptor gene polymorphisms with cocaine dependence.
Psychiatric genetics - 1 Sept 2005
Messas Guilherme, Meira-Lima Ivanor, Turchi Marília, Franco Olavo, Guindalini Camila, Castelo Adauto, Laranjeira Ronaldo, Vallada Homero
Abstract excerpt
Genetic factors play a role in the vulnerability to cocaine dependence. The reinforcing properties of cocaine are related to the dopaminergic system, and, in particular, the dopamine receptors have been linked to the reward mechanisms. The present study examines the role of the variants TaqI A of the dopamine D2 receptor gene and BalI of the dopamine D3 receptor gene in a Brazilian sample consisting of 730...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
