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Article

Induction of single chain tetracycline repressor requires the binding of two inducers.

Nucleic acids research - 1 Jan 2006

Kamionka Annette, Majewski Marius, Roth Karin, Bertram Ralph, Kraft Christine, Hillen Wolfgang

Abstract excerpt

In this article we report the in vivo and in vitro characterization of single chain tetracycline repressor (scTetR) variants in Escherichia coli. ScTetR is genetically and proteolytically stable and exhibits the same regulatory properties as dimeric TetR in E.coli. Urea-dependent denaturation of scTetR is independent of the protein concentration and follows the two-state model with a monophasic transition....

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Identifiers

PMID: 16899452
DOI: 10.1093/nar/gkl316
PMCID: PMC1557800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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