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Article

Improved tetracycline repressors for gene silencing in mycobacteria.

Nucleic acids research - 1 Apr 2009

Klotzsche Marcus, Ehrt Sabine, Schnappinger Dirk

Abstract excerpt

Tetracycline repressor (TetR)-controlled expression systems have recently been developed for mycobacteria and proven useful for the construction of conditional knockdown mutants and their analysis in vitro and during infections. However, even though these systems allowed tight regulation of some mycobacterial genes, they only showed limited or no phenotypic regulation for others. By adapting their codon usage to...

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Identifiers

PMID: 19174563
DOI: 10.1093/nar/gkp015
PMCID: PMC2665214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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