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Article

Crucial role of the small GTPase ARF6 in hepatic cord formation during liver development.

Molecular and cellular biology - 1 Aug 2006

Suzuki Teruhiko, Kanai Yoshiakira, Hara Takahiko, Sasaki Junko, Sasaki Takehiko, Kohara Michinori, Maehama Tomohiko, Taya Choji, Shitara Hiroshi, Yonekawa Hiromichi, Frohman Michael A, Yokozeki Takeaki, Kanaho Yasunori

Abstract excerpt

The mammalian small GTPase ADP-ribosylation factor 6 (ARF6) plays important roles in a wide variety of cellular events, including endocytosis, actin cytoskeletal reorganization, and phosphoinositide metabolism. However, physiological functions for ARF6 have not previously been examined. Here, we described the consequence of ARF6 ablation in mice, which manifests most obviously in the context of liver development....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16880525
DOI: 10.1128/MCB.00298-06
PMCID: PMC1592812

Genes

ARF6
HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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