Article

Arf6 Regulates Endocytosis and Angiogenesis by Promoting Filamentous Actin Assembly

2023-02-22

Abstract excerpt

<h4>ABSTRACT</h4> Clathrin-mediated endocytosis (CME) is a process vital to angiogenesis as well as general vascular homeostasis. In pathologies where supraphysiological growth factor signaling underlies disease etiology, such as in diabetic retinopathy and solid tumors, strategies to limit chronic growth factor signaling by way of CME have been shown to have tremendous clinical value. ADP ribosylation factor 6 (...

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Literature Corpus work: c664a4b1-19a8-52df-8df9-e330da17a852
DOI: 10.1101/2023.02.22.529543

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