Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of the Arf6 GDP/GTP cycle and Arf6 GTPase-activating proteins in actin remodeling and intracellular transport.

The Journal of biological chemistry - 5 May 2006

Klein Stéphanie, Franco Michel, Chardin Pierre, Luton Frédéric

Abstract excerpt

We have analyzed both biochemically and functionally a series of Arf6 mutants, providing new insights into the molecular mode of action of the small G protein Arf6. First, by comparing a fast-cycling mutant (Arf6(T157N)) and a GTPase-deficient mutant (Arf6(Q67L)), we established the necessity for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to ADP-Ribosylation Factor 6
Share to ADP-Ribosylation Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoskeleton

Share to Fluorides

Share to GTPase-Activating Proteins

Share to Guanosine Diphosphate

Share to Phospholipids

Source

Identifiers

PMID: 16527809
DOI: 10.1074/jbc.M601021200

Genes

ARHGAP10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16527809-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of the Arf6 GDP/GTP cycle and Arf6 GTPase-activating proteins in actin remodeling and intracellular transport.PMID 16527809Read ↗

Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase.Semantic proximity Read ↗

An effector domain mutant of Arf6 implicates phospholipase D in endosomal membrane recycling.Semantic proximity Read ↗

The GDP-bound form of Arf6 is located at the plasma membrane.Semantic proximity Read ↗

A regulatory role for ARF6 in receptor-mediated endocytosis.Semantic proximity Read ↗

Expression and properties of ADP-ribosylation factor (ARF6) in endocytic pathways.Semantic proximity Read ↗

A novel GTPase-activating protein for ARF6 directly interacts with clathrin and regulates clathrin-dependent endocytosis.Semantic proximity Read ↗

EFA6 facilitates the assembly of the tight junction by coordinating an Arf6-dependent and -independent pathway.Semantic proximity Read ↗

Separation of membrane trafficking and actin remodeling functions of ARF6 with an effector domain mutant.Semantic proximity Read ↗

A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements.Semantic proximity Read ↗

The small G-protein Arf6GTP recruits the AP-2 adaptor complex to membranes.Semantic proximity Read ↗

Arf6 and its role in cytoskeletal modulation.Semantic proximity Read ↗

Arf6 Regulates Endocytosis and Angiogenesis by Promoting Filamentous Actin AssemblySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.