Article
Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2.
Nature cell biology - 1 Mar 2008
Ji Peng, Jayapal Senthil Raja, Lodish Harvey F
Abstract excerpt
Mammalian erythroid cells undergo enucleation, an asymmetric cell division involving extrusion of a pycnotic nucleus enveloped by the plasma membrane. The mechanisms that power and regulate the enucleation process have remained obscure. Here, we show that deregulation of Rac GTPase during a late...
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