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Article

Betacap73-ARF6 interactions modulate cell shape and motility after injury in vitro.

Molecular biology of the cell - 1 Oct 2003

Riley Kathleen N, Maldonado Angel E, Tellier Patrice, D'Souza-Schorey Crislyn, Herman Ira M

Abstract excerpt

To understand the role that ARF6 plays in regulating isoactin dynamics and cell motility, we transfected endothelial cells (EC) with HA-tagged ARF6: the wild-type form (WT), a constitutively-active form unable to hydrolyze GTP (Q67L), and two dominant-negative forms, which are either unable to release GDP (T27N) or fail to bind nucleotide (N122I). Motility was assessed by digital imaging microscopy before Western...

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Identifiers

PMID: 14517325
DOI: 10.1091/mbc.e02-11-0726
PMCID: PMC207007

Genes

ARF6

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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