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Article

Embryonic lethality caused by apoptosis during gastrulation in mice lacking the gene of the ADP-ribosylation factor-related protein 1.

Molecular and cellular biology - 1 Mar 2002

Mueller A G, Moser M, Kluge R, Leder S, Blum M, Büttner R, Joost H-G, Schürmann A

Abstract excerpt

ADP-ribosylation factor (ARF)-related protein 1 (ARFRP1) is a membrane-associated GTPase with significant similarity to the family of ARFs. We have recently shown that ARFRP1 interacts with the Sec7 domain of the ARF-specific guanine nucleotide exchange factor Sec7-1/cytohesin and inhibits the ARF/Sec7-dependent activation of phospholipase D in a GTP-dependent manner. In order to further analyze the function of...

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Identifiers

PMID: 11839814
DOI: 10.1128/MCB.22.5.1488-1494.2002
PMCID: PMC134710

Genes

ARFRP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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