Article
JSAP1 and JLP are required for ARF6 localization to the midbody in cytokinesis.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Sept 2014
Tuvshintugs Baljinnyam, Sato Tokiharu, Enkhtuya Radnaa, Yamashita Katsumi, Yoshioka Katsuji
Abstract excerpt
The ADP-ribosylation factor 6 (ARF6) GTPase is important in cytokinesis and localizes to the midbody. However, the mechanism and regulation of ARF6's recruitment to the midbody are largely unknown. Here, we investigated the functions of two binding partners of active ARF6, c-Jun NH2 -terminal kinase (JNK)/stress-activated protein kinase-associated protein 1 (JSAP1) and JNK-associated leucine zipper protein (JLP),...
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