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Article

Localization and activation of the ARF6 GTPase during cleavage furrow ingression and cytokinesis.

The Journal of biological chemistry - 26 Jul 2002

Schweitzer Jill Kuglin, D'Souza-Schorey Crislyn

Abstract excerpt

The ARF6 GTPase mediates cell shape changes in interphase cells through its effects on membrane cycling and actin remodeling. In this study, we focus our attention on the dynamics of cell division and present evidence supporting a novel role for ARF6 during cleavage furrow ingression and cytokinesis. We demonstrate that endogenous ARF6 redistributes during mitosis and concentrates near the cleavage furrow during...

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Identifiers

PMID: 12016212
DOI: 10.1074/jbc.M201569200

Genes

ARF6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Localization and activation of the ARF6 GTPase during cleavage furrow ingression and cytokinesis.PMID 12016212Read ↗

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