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Article

Maternal methyl supplements increase offspring DNA methylation at Axin Fused.

Genesis (New York, N.Y. : 2000) - 1 Sept 2006

Waterland Robert A, Dolinoy Dana C, Lin Juan-Ru, Smith Charlotte A, Shi Xin, Tahiliani Kajal G

Abstract excerpt

Transient environmental exposures during mammalian development can permanently alter gene expression and metabolism by influencing the establishment of epigenetic gene regulatory mechanisms. The genomic characteristics that confer such epigenetic plasticity upon specific loci, however, have not been characterized. Methyl donor supplementation of female mice before and during pregnancy permanently increases DNA...

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PMID: 16868943
DOI: 10.1002/dvg.20230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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