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Article

Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring.

The Journal of nutrition - 1 Aug 2002

Cooney Craig A, Dave Apurva A, Wolff George L

Abstract excerpt

This study was designed to determine if maternal dietary methyl supplements increase DNA methylation and methylation-dependent epigenetic phenotypes in mammalian offspring. Female mice of two strains were fed two levels of dietary methyl supplement or control diet prior to and during pregnancy. Offspring of these mice vary in phenotype, which is epigenetically determined and affects health and 2-y survival....

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Identifiers

PMID: 12163699
DOI: 10.1093/jn/132.8.2393S

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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