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Article

Metastable epialleles, imprinting, and the fetal origins of adult diseases.

Pediatric research - 1 May 2007

Dolinoy Dana C, Das Radhika, Weidman Jennifer R, Jirtle Randy L

Abstract excerpt

Epigenetics is the study of the heritable changes in gene expression that occur without a change in the DNA sequence itself. These heritable epigenetic changes include chromatin folding and attachment to the nuclear matrix, packaging of DNA around nucleosomes, histone modifications, and DNA methylation. The epigenome is particularly susceptible to dysregulation during gestation, neonatal development, puberty, and...

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Identifiers

PMID: 17413847
DOI: 10.1203/pdr.0b013e31804575f7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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