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Article

Diet-induced hypermethylation at agouti viable yellow is not inherited transgenerationally through the female.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2007

Waterland Robert A, Travisano Michael, Tahiliani Kajal G

Abstract excerpt

The effects of nonmutagenic environmental exposures can sometimes be transmitted for several generations, suggesting transgenerational inheritance of induced epigenetic variation. Methyl donor supplementation of female mice during pregnancy induces CpG hypermethylation at the agouti viable yellow (A(vy)) allele in A(vy)/a offspring. Epigenetic inheritance occurs at A(vy); when passed through the female germ line,...

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PMID: 17551099
DOI: 10.1096/fj.07-8229com

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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