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Article

Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice.

PLoS genetics - 1 Apr 2006

Blewitt Marnie E, Vickaryous Nicola K, Paldi Andras, Koseki Haruhiko, Whitelaw Emma

Abstract excerpt

There is increasing evidence in both plants and animals that epigenetic marks are not always cleared between generations. Incomplete erasure at genes associated with a measurable phenotype results in unusual patterns of inheritance from one generation to the next, termed transgenerational epigenetic inheritance. The Agouti viable yellow (A(vy)) allele is the best-studied example of this phenomenon in mice. The...

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Share to DNA Methylation
Share to Epigenesis, Genetic
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Mice, Knockout

Share to Models, Genetic

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Source

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Identifiers

PMID: 16604157
DOI: 10.1371/journal.pgen.0020049
PMCID: PMC1428789

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Source receipt: pubmed, retrieved 7 Sept 2026.

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