Article
Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission.
Proceedings of the National Academy of Sciences of the United States of America - 4 Mar 2003
Rakyan Vardhman K, Chong Suyinn, Champ Marnie E, Cuthbert Peter C, Morgan Hugh D, Luu Keith V K, Whitelaw Emma
Abstract excerpt
Phenotypic variation that cannot be explained by genetic or environmental heterogeneity has intrigued geneticists for decades. The molecular basis of this phenomenon, however, is largely a mystery. Axin-fused (Axin(Fu)), first identified in 1937, is a classic example of a mammalian allele displaying extremely variable expression states. Here we demonstrate that the presence or absence of its characteristic...
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