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Article

Transposable elements: targets for early nutritional effects on epigenetic gene regulation.

Molecular and cellular biology - 1 Aug 2003

Waterland Robert A, Jirtle Randy L

Abstract excerpt

Early nutrition affects adult metabolism in humans and other mammals, potentially via persistent alterations in DNA methylation. With viable yellow agouti (A(vy)) mice, which harbor a transposable element in the agouti gene, we tested the hypothesis that the metastable methylation status of specific transposable element insertion sites renders them epigenetically labile to early methyl donor nutrition. Our...

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Identifiers

PMID: 12861015
DOI: 10.1128/MCB.23.15.5293-5300.2003
PMCID: PMC165709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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