Animal Models to Study Environmental Epigenetics1

Abstract excerpt

Epigenetics provides a means of understanding how environmental factors might alter heritable changes in gene expression without changing DNA sequence, and hence the origin, of some diseases that are not explained by conventional genetic mechanisms. Various animal models have been described, most notably the agouti viable yellow (A(vy)) and axin 1 fused (Axin1(Fu)) mice, which lend themselves particularly well to...