Article
An expression microarray approach for the identification of metastable epialleles in the mouse genome.
Epigenetics - 1 Sept 2011
Weinhouse Caren, Anderson Olivia S, Jones Tamara R, Kim Jung, Liberman Shayna A, Nahar Muna S, Rozek Laura S, Jirtle Randy L, Dolinoy Dana C
Abstract excerpt
Genetic loci displaying environmentally responsive epigenetic marks, termed metastable epialleles, offer a solution to the paradox presented by genetically identical yet phenotypically distinct individuals. The murine viable yellow agouti (A (vy) ) metastable epiallele exhibits stochastic DNA methylation and histone modifications associated with coat color variation in isogenic individuals. The distribution of A...
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