Article
An extended anaphase signaling pathway for Mad2p includes microtubule organizing center proteins and multiple motor-dependent transitions.
Cell cycle (Georgetown, Tex.) - 1 Jul 2006
Mayer Christina, Filopei Jason, Batac Joe, Alford Lea, Paluh Janet L
Abstract excerpt
Signaling pathways within the mitotic mechanism temporally orchestrate spindle assembly with chromosome capture and alignment, and then coordinate initiation of chromosome segregation with spindle breakdown and cytokinesis for reproductive success. Kinetochore localized Mad2p acts in the spindle assembly checkpoint pathway during prophase and prometaphase to monitor bipolar attachment of chromosomes to spindle...
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