Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spindle-kinetochore attachment requires the combined action of Kin I-like Klp5/6 and Alp14/Dis1-MAPs in fission yeast.

The EMBO journal - 15 Nov 2002

Garcia Miguel Angel, Koonrugsa Nirada, Toda Takashi

Abstract excerpt

Fission yeast Klp5 and Klp6 belong to the microtubule-destabilizing Kin I family. In klp5 mutants, spindle checkpoint proteins Mad2 and Bub1 are recruited to mitotic kinetochores for a prolonged duration, indicating that these kinetochores are unattached. Further analysis shows that there are kinetochores to which only Bub1, but not Mad2, localizes. These kinetochores are likely to have been captured, yet lack...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Fungal
Share to Kinesins
Share to Kinetochores

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Macromolecular Substances

Share to Metaphase

Share to Protein Interaction Mapping

Share to Schizosaccharomyces pombe Proteins

Share to Spindle Apparatus

Source

Open in PubMed Open full text

Identifiers

PMID: 12426374
DOI: 10.1093/emboj/cdf611
PMCID: PMC137203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spindle-kinetochore attachment requires the combined action of Kin I-like Klp5/6 and Alp14/Dis1-MAPs in fission yeast.PMID 12426374Read ↗

An extended anaphase signaling pathway for Mad2p includes microtubule organizing center proteins and multiple motor-dependent transitions.Semantic proximity Read ↗

Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis.Semantic proximity Read ↗

How Essential Kinesin-5 Becomes Non-Essential: Force Balance and Microtubule Dynamics MatterSemantic proximity Read ↗

How Essential Kinesin-5 Becomes Non-Essential in Fission Yeast: Force Balance and Microtubule Dynamics Matter.Semantic proximity Read ↗

Kinesin-8 from fission yeast: a heterodimeric, plus-end-directed motor that can couple microtubule depolymerization to cargo movement.Semantic proximity Read ↗

Fission yeast ch-TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpoint.Semantic proximity Read ↗

Mps1 and Ipl1/Aurora B act sequentially to correctly orient chromosomes on the meiotic spindle of budding yeast.Semantic proximity Read ↗

<i>Drosophila</i> kinesin-8 stabilises the kinetochore-microtubule interactionSemantic proximity Read ↗

Two spatially distinct Kinesin-14 Pkl1 and Klp2 generate collaborative inward forces against Kinesin-5 Cut7 in <i>S. pombe</i>Semantic proximity Read ↗

BimC motor protein KLP61F cycles between mitotic spindles and fusomes in Drosophila germ cells.Semantic proximity Read ↗

Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.Semantic proximity Read ↗

Protein complexes at the microtubule organizing center regulate bipolar spindle assembly.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.