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Article

Mps1 and Ipl1/Aurora B act sequentially to correctly orient chromosomes on the meiotic spindle of budding yeast.

Science (New York, N.Y.) - 1 Mar 2013

Meyer Régis E, Kim Seoyoung, Obeso David, Straight Paul D, Winey Mark, Dawson Dean S

Abstract excerpt

The conserved kinases Mps1 and Ipl1/Aurora B are critical for enabling chromosomes to attach to microtubules so that partner chromosomes will be segregated correctly from each other, but the precise roles of these kinases have been unclear. We imaged live yeast cells to elucidate the stages of chromosome-microtubule interactions and their regulation by Ipl1 and Mps1 through meiosis I. Ipl1 was found to release...

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Identifiers

PMID: 23371552
DOI: 10.1126/science.1232518
PMCID: PMC3604795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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