Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analyzing the spindle checkpoint in yeast and frogs.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2004

Stukenberg P Todd, Burke Daniel J

Abstract excerpt

The spindle checkpoint is an evolutionarily conserved regulatory mechanism that ensures correct segregation of chromosomes at mitosis and meiosis. The kinetochore plays an integral role in spindle checkpoint signaling by integrating chromosome attachment to the spindle with cell cycle progression. A single kinetochore can inhibit cell cycle progression in the absence of proper spindle attachment or tension from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaphase
Share to Cell Cycle
Share to Kinetochores

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitosis

Share to Saccharomyces cerevisiae

Share to Signal Transduction

Share to Spindle Apparatus

Share to Xenopus laevis

Source

Identifiers

PMID: 15187250
DOI: 10.1385/1-59259-788-2:083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analyzing the spindle checkpoint in yeast and frogs.PMID 15187250Read ↗

The spindle checkpoint: assays for the analysis of spindle checkpoint arrest and recovery.Semantic proximity Read ↗

Kinetochores and the checkpoint mechanism that monitors for defects in the chromosome segregation machinery.Semantic proximity Read ↗

An extended anaphase signaling pathway for Mad2p includes microtubule organizing center proteins and multiple motor-dependent transitions.Semantic proximity Read ↗

Analysis of kinesin motor function at budding yeast kinetochores.Semantic proximity Read ↗

New insights into the regulation of anaphase by mitotic cyclins in budding yeast.Semantic proximity Read ↗

A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embryo.Semantic proximity Read ↗

Chromosome integrity checkpoints in stem and progenitor cells: transitions upon differentiation, pathogenesis, and agingSemantic proximity Read ↗

The spindle checkpoint and chromosomal stability.Semantic proximity Read ↗

Meiotic spindle assembly checkpoint and aneuploidy in males versus femalesSemantic proximity Read ↗

Lesions in many different spindle components activate the spindle checkpoint in the budding yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

How Essential Kinesin-5 Becomes Non-Essential in Fission Yeast: Force Balance and Microtubule Dynamics Matter.Semantic proximity Read ↗

Purification of kinetochores from the budding yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.