New insights into the regulation of anaphase by mitotic cyclins in budding yeast.

doi:10.4161/cc.10.10.15632

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Article

New insights into the regulation of anaphase by mitotic cyclins in budding yeast.

Cell cycle (Georgetown, Tex.) - 15 May 2011

Signon Laurence

Abstract excerpt

Mitotic cyclins drive initiation and progression through mitosis. However, their role during progression remains poorly understood due to their essential function in initiation of mitosis and redundant activities. The function of the principal mitotic cyclin, Clb2, in S. cerevisiae, was investigated during progression through anaphase in diploid cells after DNA damage and during normal growth using fixed and live...

Topics

Anaphase
Chromosome Segregation
Cyclins
DNA Breaks, Double-Stranded
Microtubules
Mitosis
Phenotype
Rad51 Recombinase
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Spindle Apparatus

Source

Open in PubMed

Identifiers

PMID: 21512316
DOI: 10.4161/cc.10.10.15632

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