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Article

Estimating the power of variance component linkage analysis in large pedigrees.

Genetic epidemiology - 1 Sept 2006

Chen Wei-Min, Abecasis Gonçalo R

Abstract excerpt

Variance component linkage analysis is commonly used to map quantitative trait loci (QTLs) in general pedigrees. Large pedigrees are especially attractive for these studies because they provide greater power per genotyped individual than small pedigrees. We propose accurate and computationally efficient methods to calculate the analytical power of variance component linkage analysis that can accommodate large...

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PMID: 16685720
DOI: 10.1002/gepi.20160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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