Article
Robust variance-components approach for assessing genetic linkage in pedigrees.
American journal of human genetics - 1 Mar 1994
Amos C I
Abstract excerpt
To assess evidence for genetic linkage from pedigrees, I developed a limited variance-components approach. In this method, variability among trait observations from individuals within pedigrees is expressed in terms of fixed effects from covariates and effects due to an unobservable trait-affecti...
Topics
- Family
- Genetic Linkage
- Genetic Markers
- Genetic Variation
- Humans
- Mathematics
- Models, Genetic
- Nuclear Family
- Pedigree
- Probability