Exact multipoint quantitative-trait linkage analysis in pedigrees by variance components.

Abstract excerpt

Methods based on variance components are powerful tools for linkage analysis of quantitative traits, because they allow simultaneous consideration of all pedigree members. The central idea is to identify loci making a significant contribution to the population variance of a trait, by use of allele-sharing probabilities derived from genotyped marker loci. The technique is only as powerful as the methods used to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Computer Simulation
• Share to Environment