Article
Variance component methods for detecting complex trait loci.
Advances in genetics - 1 Jan 2001
Blangero J, Williams J T, Almasy L
Abstract excerpt
Variance component-based linkage analysis has become a major statistical tool for the localization and evaluation of quantitative trait loci influencing complex phenotypes. The variance component approach has many benefits--it can, for example, be used to analyze large pedigrees, and it is able to accommodate multiple loci simultaneously in a true oligogenic model. Important biological phenomena such as...
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